Supplemental Figure 1 from TCR-Based Therapy Directed against Kallikrein-Related Peptidase 4 Is Safe and Effective against Prostate Cancer

Boxplots depicting (A) SPDEF, (B) PRAC1, and (C) NKX3-1 expression in prostate cancer (TCGA data, n=30), healthy prostate (TCGA data, n=30) and across 51 (GTEx data, n=5-20) healthy tissue types, respectively. Red, green, grey and white boxplots represent prostate cancer, healthy prostate, testis and all remaining healthy tissues, respectively. Boxplots extend from first to third quartile, the horizontal line represent the median expression value. The whiskers represent the minimum and maximum expression value (1.5 IQR from the first and third quartile). Outliers are defined as being 1.5*IQR or more above the third or below the first quartile, respectively. The upper black, lower black and red dashed lines represent the median expression value, the 10 fold lower expression value and the 80 fold lower expression value, respectively. X-axis abbreviations are described in supplemental table 1. (FC: fold change, GTEx: genotype-tissue expression, IQR: interquartile range, log2-CPM: log2-transformed counts per million, TCGA: The cancer genome atlas)