Global Patterns Of Microbial Prevalence And Antibiotic Resistance: A Literature Review Highlighting Research Gaps In The Free State And Northern Cape Provinces Of South Africa

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Literature review reveals antibiotic resistance trends in Enterobacteriaceae across hospitals in South Africa, highlighting urgent research needs.

Hospital-acquired infections caused by multidrug-resistant Enterobacteriaceae pose a serious health threat in South Africa.
Significant variations in antibiotic resistance patterns, with some hospitals reporting 57.3% MDR strains among Enterobacteriaceae.
Mortality rates are alarming, with 63.8% for Carbapenem-resistant Enterobacteriaceae, particularly in low-income regions.
The lack of data on microbial prevalence in the Free State and Northern Cape emphasizes the need for targeted research to improve antibiotic stewardship.

Mkhatshwa et al. (2025) studied this question.

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Literature review reveals antibiotic resistance trends in Enterobacteriaceae across hospitals in South Africa, highlighting urgent research needs.