Crotalidae polyvalent immune Fab (ovine) dosing in Agkistrodon contortrix envenomation: a single-center retrospective cohort study

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Retrospective cohort study assesses antivenom dosing in copperhead envenomation, indicating no correlation with adverse clinical outcomes.

Core finding indicates lower doses of antivenom are used for copperhead envenomation without negative outcomes.
Data from 143 patients shows median initial antivenom dose was four vials, with 29% requiring redosing.
Study excluded patients with dry bites, those envenomated by other snakes, or without complete data.
Significance lies in potential cost savings and reevaluation of antivenom dosing strategies for copperhead envenomation.

Baumgartner et al. (2025) studied this question.

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View Full Paper

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Retrospective cohort study assesses antivenom dosing in copperhead envenomation, indicating no correlation with adverse clinical outcomes.

Core finding indicates lower doses of antivenom are used for copperhead envenomation without negative outcomes.
Data from 143 patients shows median initial antivenom dose was four vials, with 29% requiring redosing.
Study excluded patients with dry bites, those envenomated by other snakes, or without complete data.
Significance lies in potential cost savings and reevaluation of antivenom dosing strategies for copperhead envenomation.

Baumgartner et al. (2025) studied this question.

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