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August 15, 2025Folia MedicaOpen Access

Estradiol-to-testosterone ratio and erectile dysfunction in men aged 35-45

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Authors

GLGeorgi Lazarov

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Overview

Research reveals higher estradiol-to-testosterone ratios in men with erectile dysfunction, suggesting hormonal influence on sexual health.

Key Points

  • Main finding indicates a significant correlation between higher estradiol-to-testosterone ratios and erectile dysfunction in men aged 35-45.
  • Key evidence shows that the ratio in patients with erectile dysfunction ranges from 0.0042 to 0.0110, significantly higher than the control group's range.
  • The research involved 73 eugonadal men with erectile dysfunction and established controls matched by age to assess hormonal impacts.
  • Significance lies in the potential need for estradiol testing alongside testosterone to better understand and address erectile dysfunction risks.

Cite This Study

Georgi Lazarov (2025) studied this question.

synapsesocial.com/papers/689fc3ee735da01f534db9b7https://doi.org/10.3897/folmed.67.e143525
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Risk factors for hypogonadism in young men with erectile dysfunction2019 · 10 citations
  2. 2One Patient Out of Four with Newly Diagnosed Erectile Dysfunction is a Young Man—Worrisome Picture from the Everyday Clinical Practice2013 · 159 citations
  3. 3Male adiposity, sperm parameters and reproductive hormones: An updated systematic review and collaborative meta‐analysis2020 · 136 citations
  4. 4Erectile dysfunction in fit and healthy young men: psychological or pathological?2017 · 120 citations
  5. 5Relationship between penile erection and the ratio of estradiol to testosterone: A retrospective study2020 · 9 citations