Calprotectin (S100A8/A9) is not associated with ultrasound-detected synovitis in a longitudinal study of patients with psoriatic arthritis treated with biological disease-modifying anti-rheumatic drugs.
Longitudinal study assesses calprotectin's role in inflammatory activity in psoriatic arthritis, highlighting no link to ultrasound-detected synovitis.
Key Points
Calprotectin levels were higher in psoriatic arthritis patients than in controls, indicating significant inflammatory activity.
Treatment with biological disease-modifying anti-rheumatic drugs led to reduced calprotectin levels over 12 months.
No significant correlation was found between ultrasound-detected synovitis and calprotectin levels in patients.
Further research is warranted to explore the role of inflammatory markers in patients with varied inflammation levels.