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August 11, 2025Cardiology & Vascular ResearchOpen Access

Right Heart Dysfunction and Clinical Outcomes in Patients with Severe Mitral Regurgitation undergoing MitraClip

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Authors

RBRashad J. BelinNorthwestern UniversityTDTravis B. DeSaLoyola University Medical CenterIWIgor WroblewskiLoyola University Medical Center

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Implication

Assessment reveals that right heart dysfunction correlates with increased mortality in severe mitral regurgitation patients undergoing MitraClip.

Key Points

  • Patients with elevated right atrial pressure showed a 4.1 times higher risk of death after MitraClip treatment.
  • Right ventricular diastolic pressure above 10 mmHg was associated with a 13-fold increase in mortality risk.
  • This observational analysis evaluated hemodynamics and echocardiographic variables in 74 patients undergoing MitraClip.
  • Elevated pulmonary vascular resistance highlighted a need for careful assessment in severe mitral regurgitation cases.

Cite This Study

Belin et al. (2025) studied this question.

synapsesocial.com/papers/68a35efb0a429f7973328670https://doi.org/10.33425/2639-8486.1197
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic impact of right ventricular dysfunction following transcatheter mitral valve repair2021
  2. 2Right Ventricular Dysfunction and Tricuspid Regurgitation in Functional Mitral Regurgitation2021 · 18 citations
  3. 3Early response of right-ventricular function to percutaneous mitral valve repair2021 · 7 citations
  4. 4Impact and evolution of right ventricular dysfunction after successful MitraClip implantation in patients with functional mitral regurgitation2016 · 40 citations
  5. 5Integrated reverse left and right ventricular remodelling after MitraClip implantation in functional mitral regurgitation: an echocardiographic study2013 · 77 citations