August 12, 2025Sensors & DiagnosticsOpen Access

Ultrasensitive electrochemical detection of methotrexate in biological fluids using NiMn₂O₄/CNT nanocomposite-modified electrode

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The NiMn2O4/CNT-modified electrode achieved ultrasensitive detection of methotrexate in various biological fluids, showing significant promise for clinical applications.
Selectivity of the detection method reached a notable level, allowing it to identify methotrexate in complex biological samples effectively.
This study utilized a modified electrochemical approach, combining NiMn2O4 and CNT for enhanced detection performance in biological settings.
The findings support potential improvements in monitoring methotrexate levels, which could lead to better patient management and therapeutic outcomes.

Implication

Detection reveals high selectivity for methotrexate in biological fluids, indicating effectiveness of the NiMn2O4/CNT electrode.

A NiMn 2 O 4 /CNT-modified electrode enables ultrasensitive electrochemical detection of methotrexate with high selectivity in biological samples.

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Abbas et al. (2025) studied this question.

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Detection reveals high selectivity for methotrexate in biological fluids, indicating effectiveness of the NiMn2O4/CNT electrode.

A NiMn 2 O 4 /CNT-modified electrode enables ultrasensitive electrochemical detection of methotrexate with high selectivity in biological samples.