Distinct Neural Activation Patterns in Executive Functions of Schizophrenia Patients with Predominant Positive and Negative Symptoms: An fNIRS Study

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Discussion

fNIRS reveals distinct patterns in executive functions between schizophrenia patients with positive and negative symptoms.

Patients with schizophrenia showed lower accuracy in tasks, indicating poor executive function performance compared to controls.
The PSD group exhibited the highest prefrontal activation, while the NSD group had the lowest levels during tasks.
Functional near-infrared spectroscopy was used to analyze brain activity in 52 schizophrenia patients and 29 healthy controls.
Findings suggest that symptom profiles in schizophrenia influence cognitive impairments and neural mechanisms.

Xu et al. (2025) studied this question.

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