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August 15, 2025Microbes and Infectious Diseases /Microbes and Infectious DiseasesOpen Access

Biosynthesis of gold nanoparticles using local Pseudomonas aeruginosa isolates and their synergistic effects against multidrug-resistant pathogenic bacteria

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Authors

SASUAAD ABID FAZAA AL-MIYAHUniversity of Al-QadisiyahHHH.A. Alhashemi HashimAl-Furat Al-Awsat Technical UniversityAAAlaa Hashim Abd AliSouthern Federal University

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Implication

Biosynthesis of gold nanoparticles enhances antimicrobial effects against multidrug-resistant bacteria, suggesting new treatments for antibiotic resistance.

Key Points

  • Enhanced antibacterial activity observed with ciprofloxacin and gold nanoparticles against multidrug-resistant bacteria, demonstrating effective treatment synergy.
  • Gold nanoparticles were synthesized biologically using local Pseudomonas aeruginosa isolates, enabling green nanotechnology applications.
  • Assessment of nanoparticle effectiveness utilized atomic force microscopy and spectroscopy techniques to verify production and characteristics.
  • Results indicate that combining gold nanoparticles with traditional antibiotics significantly improves bacterial membrane disruption and treatment efficacy.

Cite This Study

AL-MIYAH et al. (2025) studied this question.

synapsesocial.com/papers/68a3669b0a429f797332c23chttps://doi.org/10.21608/mid.2025.370551.2646
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  4. 4Effect of Biosynthesized Gold and Silver Nanoparticles Using Alchemilla vulgaris Extract and Their Synergistic Action with Subinhibitory Concentrations of Ampicillin Against Staphylococci2026 · 2 citations
  5. 5In Vitro Investigation of Antibacterial Enhancement Using Silver and Gold Nanoparticles Against Multidrug-resistance Staphylococcus aureus2024 · 1 citations