Analysis reveals myocardial viability and perioperative ischemia impact left ventricular function in patients with ischemic dysfunction.
Background: Myocardial revascularization is the treatment of choice in patients with ischemic systolic dysfunction. Left ventricular ejection fraction (LVEF) constitutes a prognostic factor in these patients, so it is of interest to identify the variables related with left ventricular function improvement.Objective: The aim of this study is to determine the variables associated with improvement of LVEF in patients with ischemic systolic dysfunction undergoing myocardial revascularization. Methods: Patients with LVEF <50% undergoing surgical myocardial revascularization with echocardiographic monitoring ≥6months were included in the study. The variables associated with LVEF improvement >5% were analyzed. Results: The cohort consisted of 95 patients; 91.6% were men, mean age was 63 years, 40% were diabetic, 27% had previous myocardial infarction and LVEF was 36%±6%. Viability was assessed in 78% of cases. During the immediate postoperative period, 12.6% of patients presented ischemia and 28% low cardiac output. Multivariate analysis revealed that myocardial viability and lack of perioperative ischemia were independent predictors of LVEF improvement.Conclusions: Myocardial viability and absence of perioperative ischemia were associated with improved LVEF during long-term follow-up.
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Zapata et al. (2025) studied this question.
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