Why the study?
LVEF is a prognostic factor in ischemic systolic dysfunction, making it clinically relevant to identify variables associated with ventricular function improvement after myocardial revascularization.
What variables are associated with LVEF improvement >5% in patients with ischemic systolic dysfunction undergoing surgical myocardial revascularization?
What variables are associated with LVEF improvement >5% in patients with ischemic systolic dysfunction undergoing surgical myocardial revascularization?
Myocardial viability and the absence of perioperative ischemia independently predict LVEF improvement after surgical revascularization in patients with ischemic systolic dysfunction.
Viability assessment may guide CABG selection in ischemic systolic dysfunction; hypothesis-generating and requires randomized confirmation.
Background: Myocardial revascularization is the treatment of choice in patients with ischemic systolic dysfunction. Left ventricular ejection fraction (LVEF) constitutes a prognostic factor in these patients, so it is of interest to identify the variables related with left ventricular function improvement.Objective: The aim of this study is to determine the variables associated with improvement of LVEF in patients with ischemic systolic dysfunction undergoing myocardial revascularization. Methods: Patients with LVEF <50% undergoing surgical myocardial revascularization with echocardiographic monitoring ≥6months were included in the study. The variables associated with LVEF improvement >5% were analyzed. Results: The cohort consisted of 95 patients; 91.6% were men, mean age was 63 years, 40% were diabetic, 27% had previous myocardial infarction and LVEF was 36%±6%. Viability was assessed in 78% of cases. During the immediate postoperative period, 12.6% of patients presented ischemia and 28% low cardiac output. Multivariate analysis revealed that myocardial viability and lack of perioperative ischemia were independent predictors of LVEF improvement.Conclusions: Myocardial viability and absence of perioperative ischemia were associated with improved LVEF during long-term follow-up.
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Zapata et al. (2025) studied this question.
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