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August 17, 2025Al-Kufa University Journal for BiologyOpen Access

Assessment of Gene Expression Levels of Immune Markers in Celiac Desease Patients

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Authors

FAFatima Alhakeem

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Overview

This assessment reveals immune marker levels in celiac disease patients, indicating demographic links and potential immune responses.

Key Points

  • Significant downregulation of IL-1α, IL-17A, and E-selectin was found in patients with celiac disease, while TNF-α was slightly upregulated.
  • Cytokine levels were assessed in 124 celiac disease patients and 60 healthy controls, showing distinct immune responses based on age and sex.
  • The study employed serological markers and gene expression analysis through RT-PCR and ELISA to evaluate immune responses.
  • These findings suggest that younger patients and females may exhibit a more robust immune response in celiac disease.

Cite This Study

Fatima Alhakeem (2025) studied this question.

synapsesocial.com/papers/68a36a360a429f797332e4a8https://doi.org/10.36320/ajb/v17.i2.19243
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