Observational analysis shows EUS-GE improves long-term patency in malignant gastric outlet obstruction, suggesting it may replace surgical methods.
Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is emerging as a preferred approach for managing malignant gastric outlet obstruction. This technique offers a balance between the durability of surgical gastrojejunostomy (SGJ) and the minimally invasive nature of endoscopic methods. Compared to enteral stenting, EUS-GE shows superior outcomes, including higher long-term patency, lower symptom recurrence, and fewer reinterventions. It also demonstrates comparable or better efficacy than SGJ, with faster oral intake, shorter hospital stays, and reduced complications. However, EUS-GE requires specialized expertise, and long-term outcome data remain limited, so further research is needed to refine protocols and optimize patient selection.
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Antonini et al. (2025) studied this question.