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August 17, 2025Deleted Journal

Histopathology as a key to identify Sezary syndrome in patient with clinical erythroderma

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Authors

SDSonia DiovaniIIrianiwatiSFSri Awalia Febriana

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Overview

Case report highlights histopathology and immunohistochemistry in diagnosing Sezary syndrome, indicating its distinct features.

Key Points

  • Sezary syndrome diagnosis involved histopathological assessment, revealing characteristic skin features and atypical lymphocytes.
  • Clinical history indicated blistering lesions and erythroderma, with over 80% skin involvement observed in the patient.
  • Histopathological examination aids in differentiating Sezary syndrome from other conditions, despite similarities with mycosis fungoides.
  • Comprehensive diagnosis combines clinical, physical, and laboratory findings, emphasizing the role of histopathology in lymphoma cases.

Cite This Study

Diovani et al. (2025) studied this question.

synapsesocial.com/papers/68a36c270a429f797332fdaahttps://doi.org/10.22146/inajbcs.v57i3.17293
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sezary Syndrome: A Case Report and Review of Current Therapeutics2024
  2. 2Sezary syndrome initially presenting as psoriasis vulgaris, partial response after 6 cycles of gemcitabine and radiotherapy: A rare case report2025
  3. 3Flow Cytometry for Diagnosing Sézary Syndrome When Skin Biopsies Are Inconclusive: A Case Report2026
  4. 4Sézary Syndrome: Different Erythroderma Morphological Features with Proposal for a Clinical Score System2022 · 12 citations
  5. 5Sézary Syndrome in West Sweden: Exploring Epidemiology, Clinical Features, and Treatment Patterns in a Registry-Based Retrospective Analysis2024