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August 17, 2025BIO Web of ConferencesOpen Access

The effect of vitamin D supplementation on serum vitamin D and interleukin-6 levels in diabetes mellitus-induced rats

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This analysis reveals that higher vitamin D doses lower IL-6 levels in diabetic rats, suggesting immune modulation.

Higher vitamin D supplementation significantly reduced interleukin-6 levels in diabetes mellitus-induced rats, suggesting anti-inflammatory effects.
In a sample of 15 diabetic rats, serum vitamin D levels were significantly elevated at doses of 415 and 1100 IU, with p-values of 0.016 for differences.
The study employed an in vitro approach, comparing untreated rats with those given vitamin D, assessing serum markers post-treatment.
These findings imply that vitamin D may play a crucial role in managing inflammation related to diabetes, warranting further exploration.

Handayani et al. (2025) studied this question.

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