Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
February 5, 2026

The effect of vitamin D supplementation on serum vitamin D and interleukin-6 levels in diabetes mellitus-induced rats

View Full Paper
Ask AI
Bookmark
Share

Authors

KHKurnia Maidarmi HandayaniWSWidia SariUniversitas BaiturrahmahRHRendri Bayu HansahUniversitas Baiturrahmah

Discussion

Loading...

Member takes

Implication

In vitro study investigates vitamin D's impact on serum vitamin D and IL-6 levels in diabetes-induced rats, suggesting potential anti-inflammatory benefits.

Key Points

  • The study aimed to assess the impact of varying doses of vitamin D on serum vitamin D and IL-6 levels in diabetes mellitus-induced rats.
  • Conducted an in vitro study on 15 diabetic rats divided into three treatment groups.
  • One group received no treatment, another received 415 IU, and the last received 1100 IU of oral vitamin D.
  • Measured serum vitamin D and IL-6 levels post-treatment.
  • Significant differences in serum vitamin D levels were noted among treatment groups (p = 0.016).
  • ANOVA revealed significant differences in IL-6 levels among groups (p = 0.017).
  • A negative correlation was found between serum vitamin D and IL-6 levels (r= -0.542, p=0.037).

Cite This Study

Handayani et al. (2025) studied this question.

synapsesocial.com/papers/698433baf1d9ada3c1fb11dahttps://doi.org/10.1051/bioconf/202518401004/pdf
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The effect of vitamin D supplementation on serum vitamin D and interleukin-6 levels in diabetes mellitus-induced rats2025
  2. 2Vitamin D Ameliorative Effect on some Immunological Aspects of Type II Diabetes Mellitus in Rat Model2024
  3. 3Effects of Vitamin D Supplementation on Blood Glucose Levels in Streptozotocin-Induced Diabetic Rats2025 · 1 citations
  4. 4P20 - Phase-dependent effects of vitamin D on oxidative and immune pathways in a rat model of diabetes mellitus2025
  5. 5Correlation of vitamin D levels with TNF-α and IL-6 expression in insulin-resistant type 2 diabetes mellitus patients2026