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August 17, 2025

Temporal trends and projections of the global burden of osteoarthritis derived from the Global Burden of Disease 2021 study

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Authors

WZWentao ZhaoZhejiang Institute of Mechanical and Electrical EngineeringFLFeng LiJinzhong UniversityYHYunfei HouFudan University Shanghai Cancer Center

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Implication

Analysis reveals rising osteoarthritis prevalence and incidence, highlighting health inequities and aging effects.

Key Points

  • Global osteoarthritis cases rose from 20.9 million to 46.6 million since 1990, which represents a major increase in burden.
  • Prevalence surged from 256 million to 606 million cases over the same period, indicating significant health challenges.
  • Joinpoint regression and age-period-cohort models were applied to assess the trends and analyze health disparities.
  • The increase in osteoarthritis burden is linked to population aging and rising obesity rates, requiring targeted interventions.

Cite This Study

Zhao et al. (2025) studied this question.

synapsesocial.com/papers/68a36de60a429f797333187ehttps://doi.org/10.21203/rs.3.rs-7057886/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Global, regional, and national burden of osteoarthritis in elderly from 1990 to 2021: Insights from the global burden of disease study 20212026
  2. 2Epidemiological trends of osteoarthritis at the global, regional, and national levels from 1990 to 2021 and projections to 20502024 · 8 citations
  3. 3Global Burden, Demographic and Geographic Disparities of Osteoarthritis by Joint Site Among Adults Aged 55 Years and Older, 1990–20212026
  4. 4Temporal Trends and Cross‐Country Inequalities in the Burden of Osteoarthritis, 1990–2021: Findings From the Global Burden of Disease Study 20212026
  5. 5Global, regional, and national disease burden of hip osteoarthritis and its predicted level to 2050: an epidemiological analysis from 1990 to 20212026