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August 17, 2025RSC Medicinal Chemistry20 citations

Leveraging Artificial Intelligence and Machine Learning in Kinase Inhibitor Development: Advances, Challenges, and Future Prospects

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MEMohamed Saleh ElgawishSZSawsan A. ZaitoneAAAya M. Almatary

Key Points

  • AI and machine learning technologies enhance the development of kinase inhibitors for cancer and autoimmune disorders, improving treatment options.
  • Recent advancements highlight that integrating AI can lead to significant breakthroughs in kinase inhibitor therapies, particularly in cancer management.
  • Observational analysis demonstrates the clinical relevance of protein kinases in disease progression, making them key targets for new therapies.
  • The study emphasizes the potential of AI and machine learning methodologies to streamline the drug development process, which may lead to faster therapeutic interventions.

Abstract

Protein kinases are central regulators of cell signaling and play pivotal roles in a wide array of diseases, most notably cancer and autoimmune disorders. The clinical success of kinase inhibitors—such...

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Cite This Study

Elgawish et al. (2025) studied this question.

synapsesocial.com/papers/68a36dec0a429f79733318d1https://doi.org/10.1039/d5md00494b
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