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August 17, 2025International Journal of Research and Innovation in Applied Science

Pharmacokinetic Studies and Molecular Docking Studies of the Anti-Ulcer Potential of Musa Sapientum Phytocompunds

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Authors

EDEmmanuel Markus DearslyEDEmmanuel Damilo DadaOOOshatuyi Olukayode

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Overview

This study reveals strong anti-ulcer properties of phytocompounds, suggesting effective alternatives to standard treatments for peptic ulcer disease.

Key Points

  • Musa sapientum phytocompounds showed strong anti-ulcer potential, indicating a viable alternative to proton pump inhibitors.
  • Epicatechin and Gallocatechin demonstrated binding affinities surpassing Lansoprazole and Omeprazole in molecular docking studies.
  • Analysis highlighted that most active compounds fulfilled criteria for oral bioavailability, showing promising pharmacokinetic profiles.
  • Concerns remain for 1,8-Diethoxyanthracene-9,10-dione due to safety risks, while other compounds exhibited favorable drug-likeness and minimal toxicity.

Cite This Study

Dearsly et al. (2025) studied this question.

synapsesocial.com/papers/68a36dec0a429f7973331a53https://doi.org/10.51584/ijrias.2025.100700071
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Therapeutic Potentials of Phytoconstituents of Asparagus racemosus and Ocimum gratissimum Plants for Treatment of Peptic Ulcer Disease2025
  2. 2Phytochemistry and Biological Activities of Ethnopharmacological Plants Widely Used in the Treatment of Pectic Ulcer Diseases2024 · 4 citations
  3. 3Antiulcer Activity of Aqueous Peel Extract of Musa Sapientum in Albino Rats2026
  4. 4A Review on Herbal Potential for Treatment of Peptic Ulcer2025 · 1 citations
  5. 5A Systematic Review on Exploration of Extracts and Phytochemicals for Peptic Ulcer from 2018 to 20242026