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August 17, 2025International Journal of Molecular SciencesOpen Access

Evaluation of a Classifier Based on Calprotectin Concentration and Advanced Glycation End-Product Receptor as a Potential Biomarker for Abdominal Aortic Aneurysm

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Authors

WHWilly HauzerPHPaula HauzerTKTomasz Klimek

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Overview

Evaluation finds calprotectin elevates AAA risk in patients, indicating potential for biomarker use in screening.

Key Points

  • Calprotectin concentration significantly predicts abdominal aortic aneurysm (AAA), indicating inflammation's role.
  • The decision tree model showed over 100 times greater likelihood of AAA with elevated calprotectin and sRAGE levels.
  • Statistical analysis used included Mann–Whitney U test and the Hosmer-Lemeshow test for group comparisons.
  • Exploration of non-invasive measures for biomarker monitoring could enhance AAA screening efforts.

Cite This Study

Hauzer et al. (2025) studied this question.

synapsesocial.com/papers/68a36f7d0a429f7973331ce8https://doi.org/10.3390/ijms26167752
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