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December 26, 2019Biotechnology and Applied Biochemistry

High‐performance detection of an abdominal aortic aneurysm biomarker by immunosensing

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Population

In vitro detection of Insulin-like growth factor 1 (IGF-1) as a biomarker for abdominal aortic aneurysm

Comparison

Immunosensing using an InterDigitated electrode… vs Related protein controls (IGF-2 and IGFBP3)

Design

Preclinical

Authors

SGShikui GuoYLYuejin LiRLRougang Li

Discussion

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Overview

May aid AAA biomarker discovery; leaves open clinical translation pending validation studies.

Structured PICO

P
Population
In vitro detection of Insulin-like growth factor 1 (IGF-1) as a biomarker for abdominal aortic aneurysm
I
Intervention
Immunosensing using an InterDigitated electrode (IDE) sensor
C
Comparator
Related protein controls (IGF-2 and IGFBP3)
O
Outcome
Detection limit and selectivity for IGF-1surrogate

An IDE immunosensor can detect the AAA biomarker IGF-1 with high sensitivity (100 fM) and selectivity, offering a potential cost-effective diagnostic platform.

Cite This Study

Guo et al. (2019) studied this question.

synapsesocial.com/papers/6a912685b22c78c91f81c46ahttps://doi.org/10.1002/bab.1877
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Analyzing duplex formation with abdominal aortic aneurysm biomarker on palladium nanocube attached interdigitated electrodes2026
  2. 2Biomarkers And Screening Tests For Abdominal Aortic Aneurysm: A Brief Review2009 · 1 citations
  3. 3Identification and Validation of Plasma Protein Biomarkers for Abdominal Aortic Aneurysm Using Integrated Proteomics2026
  4. 4Identification and Evaluation of Blood-Based Biomarkers for Abdominal Aortic Aneurysm2024 · 6 citations
  5. 5Evaluation of a Classifier Based on Calprotectin Concentration and Advanced Glycation End-Product Receptor as a Potential Biomarker for Abdominal Aortic Aneurysm2025