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August 17, 2025Bioinformation

Molecular markers in triple-negative breast cancer: A retrospective correlation study

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High positivity of Ki-67 and p53 indicated a higher tumor grade, enhancing risk of metastasis.
Key findings showed that elevated expression of EGFR and CK5/6 was linked to poor differentiation in triple-negative breast cancer.
The observational analysis utilized immunohistochemistry to assess molecular markers in tissue samples from 128 patients.
These results may guide future targeted therapies in managing triple-negative breast cancer for better patient outcomes.

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Retrospective study shows higher levels of Ki-67 and p53 in patients with triple-negative breast cancer, suggesting implications for prognosis.

Gupta et al. (2025) studied this question.

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Retrospective study shows higher levels of Ki-67 and p53 in patients with triple-negative breast cancer, suggesting implications for prognosis.