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August 17, 2025Brain SciencesOpen Access

Cerebral Microbleeds with a Venous Connection on 3 Tesla Susceptibility-Weighted Imaging in Persons with Alzheimer’s Disease and Healthy Aging Controls

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Authors

UJUlf Jensen‐KonderingUniversity Hospital Schleswig-HolsteinVKVéronique KuhnUniversity of LübeckHSHannes SchachtUniversity Hospital Schleswig-Holstein

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Implication

Analysis of cerebral microbleeds reveals no difference in prevalence between Alzheimer’s patients and healthy aging controls, suggesting a shared vascular component.

Key Points

  • Cerebral microbleeds with venous connections are present in both Alzheimer’s and healthy individuals, highlighting possible commonality.
  • A total of 571 participants were assessed, with 367 cerebral microbleeds identified across both groups, showing prevalence rates of 6.6% for AD and 7.4% for controls.
  • Logistic regression indicates a statistically significant association between the presence of CMBven and higher CMB load, particularly among females.
  • Further investigations are needed to explore the histopathology and clinical significance of CMBven in these populations.

Cite This Study

Jensen‐Kondering et al. (2025) studied this question.

synapsesocial.com/papers/68a36f8a0a429f7973332517https://doi.org/10.3390/brainsci15080851
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ABSTRACT NUMBER: ESOC2026A2117 ASSOCIATIONS OF CEREBRAL MICROBLEEDS IN CADASIL2026
  2. 2Associations Between Cerebral Microbleed Patterns and Incident Dementia: The ARIC-Neurocognitive Study2026 · 2 citations
  3. 3Cerebral Microbleeds and Superficial Siderosis: Vascular Correlates and Cognition in a Memory Clinic2026
  4. 4Cerebral Microbleeds Associate with Brain Endothelial Cell Activation-Dysfunction and Blood-Brain Barrier Dysfunction-Disruption with an Increased Risk of Hemorrhagic and Ischemic Stroke That Is Capable of Exacerbating Neurodegeneration2024 · 6 citations
  5. 5Association Between Cognitive Impairment and Multimodal MRI Markers in Patients with Cerebral Microbleeds: A Retrospective Case–Control Study2026