What type of study is this?

This is a In Vitro Study study.

Identification of phytochemicals as potential inhibitors against E6 protein of High-Risk Human Papillomavirus 16(HPV 16) via In-Silico Structure-Based Virtual Screening Approach

View Full Paper

Ask AI

Bookmark

Authors

Virtual screening identified three phytochemical inhibitors targeting E6 protein in HPV 16, suggesting new anti-cancer strategies.

Three phytochemicals were identified as potential inhibitors of the E6 protein, which is crucial for HPV-related cancer development.
Binding energy and hydrogen bond interactions were key metrics in selecting these inhibitors from a library of 2296 compounds.
Molecular dynamics simulations over 100ns confirmed the stability of the docked complexes with the E6 protein.
This research highlights the potential of these compounds in advancing anti-HPV therapeutic options in cancer treatment.

Arshad Jamal (2023) studied this question.

View Full Paper

Ask AI

Bookmark