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August 17, 2025Advancements in Life SciencesOpen Access

Value of Serum Inhibin B as a Prognostic Factor in Patients with Non-obstructive Azoospermia

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Authors

AAAli A. Abo-AlshaarHAHind AbdulkadimWMWalaa Saeb Mejbel

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Overview

Cross-sectional analysis evaluates serum inhibin B's effectiveness for predicting sperm retrieval in men with non-obstructive azoospermia, highlighting its limited predictive ability.

Key Points

  • Inhibin B levels were significantly higher in TESE successful patients, but predictive accuracy remained low.
  • The median serum inhibin B for positive sperm retrieval was 54.7 pg/ml compared to 24 pg/ml in negative cases.
  • Cross-sectional study included 188 men with non-obstructive azoospermia and excluded those with obstructive forms.
  • While inhibin B shows potential, its sensitivity of 70.9% and specificity of 50% need improvement for better prognosis.

Cite This Study

Abo-Alshaar et al. (2023) studied this question.

synapsesocial.com/papers/68a370e80a429f7973333348https://doi.org/10.62940/als.v10i0.2003
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1(183) The Predictive Value of AMH, FSH, and Inhibin B for Sperm Retrieval in Azoospermic Men2024
  2. 2Testicular histopathology and follicular stimulating hormone to predict fertility in nonobstructive azoospermia2024 · 1 citations
  3. 3Estimation of B-inhibin and anti mullerian hormone in functional azoospermia and their correlations with surgical sperm retrieval: A prospective case-control study2024
  4. 4Testosterone-to-Follicle Stimulating Hormone Ratio Predicts Sperm Retrieval Success in Men with Idiopathic Non-Obstructive Azoospermia.2026
  5. 5Serum inhibin B levels reflect Sertoli cell function in normal men and men with testicular dysfunction.1996 · 394 citations