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August 21, 2025MedicineOpen Access

Genetically predicted the causal relationship between blood metal levels and ischemic stroke risk based on Asian ethnicity

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Mendelian randomization reveals that elevated calcium increases ischemic stroke risk in Asians, highlighting blood metal monitoring.

Elevated plasma calcium levels increase the risk of ischemic stroke, indicating a need for blood metal monitoring.
Plasma chromium levels appear to offer a protective effect against ischemic stroke, suggesting possible intervention strategies.
Using 2-sample Mendelian randomization, causal relationships were established for 42 blood metals related to stroke risk.
Research highlights the importance of blood metal concentrations as potential preventive measures for ischemic stroke.

Jing et al. (2025) studied this question.

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