Observational analysis finds higher risk of ischemic stroke in patients with peridevice leak, emphasizing its significance in left atrial appendage closure outcomes.
Key Points
Patients with peridevice leak showed a significantly higher risk of transient ischemic attack, ischemic stroke, or systemic embolism, highlighting the importance of managing leaks.
Among 1397 patients, 84 had peridevice leak, with 73 having ≤3 mm leaks, underscoring that even small leaks can impact outcomes.
Analysis utilized Fine and Gray multivariable regression and propensity score matching to compare outcomes between groups with and without peridevice leak.
These findings indicate that achieving no peridevice leak may be crucial for reducing the risk of serious complications post-closure.