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August 18, 2025Frontiers in NutritionOpen Access

Human milk vs. cow-milk based infant formula proteins: structure, digestion and physiological impacts

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Review highlights protein composition and digestion effects on infants, suggesting improvements in infant formula for better health outcomes.

Human milk shows distinct protein composition influencing digestion and health in infants, unlike infant formula.
Key differences include the non-protein nitrogen fraction, which is crucial yet often overlooked in formulations.
Assessment of protein digestion mechanisms reveals varying amino acid absorption rates in infants between both milk types.
Focus on partially digested proteins may enhance understanding of infant gut microbiota and overall health.

Chauvet et al. (2025) studied this question.

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Review highlights protein composition and digestion effects on infants, suggesting improvements in infant formula for better health outcomes.