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August 18, 2025ACS Applied Polymer Materials

Fabrication of Zwitterionic Copolymer and Ag Nanoparticle Coating for Enhanced Antibiofouling and Bactericidal Properties

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Authors

CHChuangxin HuangXLXin LiuZGZhan Gao

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Overview

This research demonstrates that modified titanium implants reduce biofouling and enhance bactericidal properties, suggesting significant clinical potential.

Key Points

  • The engineered Ti/PDA–PSB@Ag0.15 coating achieved over 99.9% bacterial inhibition against E. coli and S. aureus, ensuring effective antibacterial action.
  • Exposure to the coating showed high fibroblast viability greater than 90%, confirming its safety for biological applications.
  • An accelerated deposition strategy reduced the polymerization time significantly from 24 hours to just 4 hours, enhancing efficiency in coating processes.
  • The modified titanium exhibited low hemolysis (<3%) and effective anticoagulation, marking it as a promising solution for biomedical applications.

Cite This Study

Huang et al. (2025) studied this question.

synapsesocial.com/papers/68af4546ad7bf08b1ead30a7https://doi.org/10.1021/acsapm.5c01897
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