What question did this study set out to answer?

To evaluate the cytocompatibility, antimicrobial performance, and surface properties of multilayer chitosan-based smart coatings deposited onto silver-decorated titania nanotubes.

September 20, 2023Journal of Biomedical Materials Research Part B Applied BiomaterialsOpen Access

Cytocompatibility, antibacterial, and corrosion properties of chitosan/polymethacrylates and chitosan/poly(4‐vinylpyridine) smart coatings, electrophoretically deposited on nanosilver‐decorated titania nanotubes

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Authors

ŁPŁukasz Pawłowski MBMichał Bartmański ARAnna Ronowska

Discussion

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Overview

In vitro study demonstrates high antibacterial efficacy and biocompatibility of polymer-coated titania nanotubes, suggesting promising protection against implant infections.

Key Points

To evaluate the cytocompatibility, antimicrobial performance, and surface properties of multilayer chitosan-based smart coatings deposited onto silver-decorated titania nanotubes.
Fabricated titania nanotubes via electrochemical oxidation and decorated the surface with silver nanoparticles through electrochemical reduction of silver nitrate.
Applied composite biopolymer coatings of chitosan with Eudragit E 100 or poly(4-vinylpyridine) using electrophoretic deposition.
Characterized morphology, silver release, corrosion resistance, antibacterial efficacy against Gram-positive and Gram-negative bacteria, and cytocompatibility using hFOB 1.19 human osteoblasts.
Biopolymer deposition produced tightly coated surfaces over nanotubes (diameter 97 ± 12 nm, length 342 ± 36 nm) and reduced the burst release of silver.
Coated surfaces exhibited strong antibacterial activity, achieving 99.9% total elimination of Escherichia coli with the chitosan/poly(4-vinylpyridine) coating.
Human osteoblast (hFOB 1.19) growth at day 3 was unaffected by the modifications compared to unmodified titanium controls.

Cite This Study

Pawłowski et al. (2023) studied this question.

synapsesocial.com/papers/6a7187396ceb2bbd16e02d23 https://doi.org/10.1002/jbm.b.35332

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September 20, 2023Journal of Biomedical Materials Research Part B Applied BiomaterialsOpen Access

Cytocompatibility, antibacterial, and corrosion properties of chitosan/polymethacrylates and chitosan/poly(4‐vinylpyridine) smart coatings, electrophoretically deposited on nanosilver‐decorated titania nanotubes

View Full Paper

Ask AI

Bookmark

Authors

ŁPŁukasz Pawłowski MBMichał Bartmański ARAnna Ronowska

Discussion

Member takes

Overview

In vitro study demonstrates high antibacterial efficacy and biocompatibility of polymer-coated titania nanotubes, suggesting promising protection against implant infections.

Key Points

To evaluate the cytocompatibility, antimicrobial performance, and surface properties of multilayer chitosan-based smart coatings deposited onto silver-decorated titania nanotubes.
Fabricated titania nanotubes via electrochemical oxidation and decorated the surface with silver nanoparticles through electrochemical reduction of silver nitrate.
Applied composite biopolymer coatings of chitosan with Eudragit E 100 or poly(4-vinylpyridine) using electrophoretic deposition.
Characterized morphology, silver release, corrosion resistance, antibacterial efficacy against Gram-positive and Gram-negative bacteria, and cytocompatibility using hFOB 1.19 human osteoblasts.
Biopolymer deposition produced tightly coated surfaces over nanotubes (diameter 97 ± 12 nm, length 342 ± 36 nm) and reduced the burst release of silver.
Coated surfaces exhibited strong antibacterial activity, achieving 99.9% total elimination of Escherichia coli with the chitosan/poly(4-vinylpyridine) coating.
Human osteoblast (hFOB 1.19) growth at day 3 was unaffected by the modifications compared to unmodified titanium controls.

Cite This Study

Pawłowski et al. (2023) studied this question.

synapsesocial.com/papers/6a7187396ceb2bbd16e02d23 https://doi.org/10.1002/jbm.b.35332

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