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This is a Literature Review study.

August 19, 2025CellsOpen Access

Nonsense-Mediated mRNA Decay: Mechanisms and Recent Implications in Cardiovascular Diseases

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Review highlights NMD implications in cardiovascular disease, suggesting potential therapeutic avenues for treatment.

Nonsense-mediated mRNA decay (NMD) plays a crucial role in regulating gene expression in cardiovascular diseases.
Key components of NMD include up-frameshift proteins and eukaryotic release factors, essential for mRNA surveillance.
Understanding NMD's mechanisms may pave the way for personalized medicine strategies in cardiovascular therapy.
Dysregulation of NMD is linked to various diseases, underscoring its potential impact on cardiovascular health.

Hassan et al. (2025) studied this question.

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