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August 1, 2025BMJ OpenOpen Access

Independent and joint association of accelerometer-measured sedentary behaviour and physical activity with mild cognitive impairment and intrinsic capacity decline among Chinese older adults: study protocol for a cross-sectional study

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Authors

QZQing ZhaoQWQi-Zhen WuRLRobert Lai

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Overview

Cross-sectional study explores sedentary behaviour and physical activity effects on cognitive function and intrinsic capacity in older adults, suggesting significant associations.

Key Points

  • Sedentary behaviour correlates with higher risk of mild cognitive impairment in older adults, while physical activity may provide protective effects.
  • Participants aged 65 and older will be monitored using accelerometers for a week to measure their activity levels and sedentary time.
  • Cross-sectional observational design will analyze the joint impact of sedentary behaviour and physical activity on cognitive decline across different age groups.
  • Findings may indicate the need for targeted interventions to enhance intrinsic capacity and cognitive health among older populations.

Cite This Study

Zhao et al. (2025) studied this question.

synapsesocial.com/papers/68af494dad7bf08b1ead4c27https://doi.org/10.1136/bmjopen-2024-097806
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sedentary behavior and cognitive impairment risk in older Chinese adults: effect modification by physical activity2026
  2. 2Association between physical activity and sedentary behaviour and changes in intrinsic capacity in Spanish older adults (Seniors-ENRICA-2): a prospective population-based study2025 · 23 citations
  3. 3Moderate-to-vigorous physical activity and cognition among older adults in China: Mediation by depressive symptoms and moderation by age2026 · 1 citations
  4. 4Multi-trajectories of activity participation and risk of mild cognitive impairment in China: A national longitudinal cohort study2026
  5. 5Association between physical activity levels and intrinsic capacity impairment among Chinese older adults: A cross-sectional study based on CHARLS2026