Supplementary Figure S6 from Mutational Analysis of Early, Low-Grade Bowel Polyps Defines a Subgroup with Concurrent, High-Risk Oncogenic Drivers Independent of Polyp Size

Venn diagram to show the intersection between CRC carrying mutations in WNT, RAS and TP53 pathway from TCGA adenocarcinoma dataset. "total" indicates the whole sample set of TCGA COAD/READ. "WNT" depicts the CRC that carries oncogenic mutations in WNT pathway genes. "RAS" depicts CRC samples that have oncogenic mutations in RTK-RAS pathway genes. "P53" depicts CRC samples that have oncogenic mutations in TP53 pathway genes. All three pathways refer to the definition in The Cancer Genome Atlas Network paper (Nature 487, 330–337 (2012)).