Observational analysis highlights potential risk of antimicrobial resistance in sexual networks with doxycycline prophylaxis.
Doxycycline post-exposure prophylaxis (doxyPEP) is now included in many clinical guidelines, yet concerns remain regarding antimicrobial resistance (AMR), particularly off-target effects on commensal bacteria in the oropharynx, with intimate behaviours potentially facilitating resistance transmission within sexual networks.
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Roberts et al. (2025) studied this question.
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