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This is a Observational study (also classified as: Literature Review).

August 20, 2025PeerJOpen Access

Transformative insights from transcriptome analysis of colorectal cancer patient tissues: identification of four key prognostic genes

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Analysis identifies four key prognostic genes in colorectal cancer, suggesting enhanced therapeutic strategies.

The identified four prognostic genes associated with poor overall survival in colorectal cancer patients, highlighting their clinical significance.
Patients categorized into low-risk and high-risk groups showed significantly poorer overall survival in the high-risk category.
Using multivariate Cox regression, a predictive risk score was developed based on differential gene expression data.
Integrative analysis of transcriptome data with publicly available datasets enhances understanding of CRC pathology.

Belder et al. (2025) studied this question.

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August 20, 2025PeerJOpen Access

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Authors

Analysis identifies four key prognostic genes in colorectal cancer, suggesting enhanced therapeutic strategies.

The identified four prognostic genes associated with poor overall survival in colorectal cancer patients, highlighting their clinical significance.
Patients categorized into low-risk and high-risk groups showed significantly poorer overall survival in the high-risk category.
Using multivariate Cox regression, a predictive risk score was developed based on differential gene expression data.
Integrative analysis of transcriptome data with publicly available datasets enhances understanding of CRC pathology.

Belder et al. (2025) studied this question.

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