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This is a Literature Review study.

August 19, 2025Open Access

Intestinal Permeability Markers in Depression – A Narrative Review

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Altered intestinal permeability markers may be linked to depression, yet findings vary widely across studies.
Key markers include zonulin, lipopolysaccharides, and soluble CD14, indicating their potential role in depression.
Analysis reveals challenges such as small sample sizes affecting the interpretation of findings and consistency.
While markers show promise in identifying inflammation-related depression subtypes, their clinical use is not yet supported.

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Implication

Narrative review highlights inconsistent findings on intestinal permeability markers in depression patients, suggesting complexity in patient stratification.

Cite This Study

Bibolar et al. (2025) studied this question.

synapsesocial.com/papers/68af4eb4ad7bf08b1ead7545 https://doi.org/10.20944/preprints202508.1326.v1

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Implication

Narrative review highlights inconsistent findings on intestinal permeability markers in depression patients, suggesting complexity in patient stratification.

Intestinal Permeability Markers in Depression – A Narrative Review

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Discussion

Implication

Cite This Study

Intestinal Permeability Markers in Depression – A Narrative Review

Key Points

Discussion

Implication

Cite This Study

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