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This review aims to explore the mechanisms by which intestinal flora influence depression and evaluate therapeutic approaches.

Intestinal Flora and Depression: Interaction Mechanisms and Therapeutic Prospects

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This review aims to explore the mechanisms by which intestinal flora influence depression and evaluate therapeutic approaches.
Summarization of existing research on intestinal flora and depression.
Focus on pathophysiological mechanisms and microbial activities.
Discussion of current therapeutic strategies targeting intestinal flora.
Identified specific pathways where intestinal flora affect depression.
Highlighted the role of microbial dysbiosis in depression.
Outlined potential therapeutic strategies that target gut microbiota.

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Review assesses how intestinal flora affects depression, suggesting new therapeutic strategies to improve outcomes.

Zhang et al. (2026) studied this question.

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