What type of study is this?

This is a Observational study (also classified as: Case Report).

August 21, 2025DiagnosticsOpen Access

Association of TCF7L2 rs7903146 (C/T) Polymorphism with Type 2 Diabetes Mellitus in a Chinese Population: Clinical Characteristics and Ethnic Context

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Authors

YLYung‐Chuan LuNational Yang Ming Chiao Tung University TYTeng‐Hung YuI-Shou University CHChin‐Feng HsuanE-Da Hospital

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Implication

Case-control analysis reveals TCF7L2 rs7903146 links to T2DM and elevated fasting glucose in Han Chinese cohorts, suggesting broader ethnic implications.

Key Points

The TCF7L2 rs7903146 T allele increases the risk of type 2 diabetes mellitus in this cohort.
Adjusted odds ratio for the CT/TT genotypes was 2.24, indicating a significant association with T2DM.
Analysis included 600 diabetic patients and 511 controls, utilizing logistic regression under a dominant model.
Findings may point to metabolic pathways impacted by TCF7L2, suggesting need for further validation.

Cite This Study

Lu et al. (2025) studied this question.

synapsesocial.com/papers/68af4ec6ad7bf08b1ead81e9 https://doi.org/10.3390/diagnostics15162110

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Implication

Case-control analysis reveals TCF7L2 rs7903146 links to T2DM and elevated fasting glucose in Han Chinese cohorts, suggesting broader ethnic implications.

Association of TCF7L2 rs7903146 (C/T) Polymorphism with Type 2 Diabetes Mellitus in a Chinese Population: Clinical Characteristics and Ethnic Context

Discussion

Member takes

Implication

Key Points

Cite This Study

Association of TCF7L2 rs7903146 (C/T) Polymorphism with Type 2 Diabetes Mellitus in a Chinese Population: Clinical Characteristics and Ethnic Context

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

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