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August 15, 2025International Journal of Molecular SciencesOpen Access

GC-MS-Identified Alkamides and Evaluation of the Anti-Inflammatory, Antibacterial, and Antioxidant Activities of Wild Acmella radicans

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Authors

IHIsrael Hurtado‐DíazRTRubicela Teta-TalixtactaABAntonio Bernabé‐Antonio

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Overview

Chemical analysis reveals alkamides' anti-inflammatory and antibacterial effects in Acmella radicans extracts, suggesting medicinal potential.

Key Points

  • Significant inhibition of nitric oxide production was observed, with levels reduced to 22.2 ± 1.9 μM for both root and aerial extracts.
  • Evaluated fractions showed notable inhibition of TNF-α production, lowering to 22.6 ± 3.3 pg/mL for aerial extracts at 25 µg/mL.
  • Analysis using gas chromatography–mass spectrometry (GC-MS) identified key alkamides in both root and aerial fractions.
  • Moderate antibacterial activity was noted against S. typhimurium, emphasizing the medicinal value of Acmella radicans extracts.

Cite This Study

Hurtado‐Díaz et al. (2025) studied this question.

synapsesocial.com/papers/68af509bad7bf08b1ead8833https://doi.org/10.3390/ijms26167884
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