August 15, 2025Open Access

Bridging genes and therapy : insights into CBT outcomes for OCD, anxiety and depression

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JBJulia BobergUppsala University

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Implication

Analysis shows polygenic scores impact CBT-related symptom reduction in anxiety, OCD, and depression patients, suggesting genetic influences on therapy effectiveness.

Key Points

Higher polygenic scores for educational attainment are linked with better outcomes in individuals undergoing CBT for anxiety and depression.
Study examined genetic associations among 3,113 individuals with psychiatric disorders receiving CBT, providing important insights into treatment variability.
Research indicates common genetic variation plays a modest role in treatment outcomes, though specific markers require larger datasets for detection.
Rare genetic variants were identified in individuals with OCD, suggesting a significant influence on symptom severity and treatment response.

Cite This Study

Julia Boberg (2025) studied this question.

synapsesocial.com/papers/68af50a1ad7bf08b1ead89fb https://doi.org/10.69622/29170409.v1

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Implication

Analysis shows polygenic scores impact CBT-related symptom reduction in anxiety, OCD, and depression patients, suggesting genetic influences on therapy effectiveness.

Bridging genes and therapy : insights into CBT outcomes for OCD, anxiety and depression

Discussion

Member takes

Implication

Key Points

Cite This Study

Bridging genes and therapy : insights into CBT outcomes for OCD, anxiety and depression

Discussion

Member takes

Implication

Key Points

Cite This Study

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