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Clinicopathological analysis identifies pancreatic cancer types and raising awareness of vascular invasion in patients undergoing gastroduodenopancreatectomy.
Objective: To describe the clinical characteristics of patients who underwent gastroduodenopancreatectomy between 2022 and 2024 at a university hospital, as well as the histopathological findings of their surgical specimens. Methods: Biopsy request forms and histopathological reports were reviewed in the digital archives of the Pathology Unit of a university hospital. The information analyzed was: age, sex, frozen section biopsy, histopathological report, margin assessment, lymphatic, blood and neural vascular invasion and tumor size. Results: During this period, 37 gastroduodenopancreatectomy surgeries were performed in this hospital, with an average patient age of 58 years (SD=12.6), 27 (72.9%) of which were female and 10 (27.0%) were male. Thirty-two (86.4%) patients had malignant lesions, with the most prevalent histopathological diagnoses being pancreatic ductal adenocarcinoma (21.6%) followed by intestinal type adenocarcinoma (18.9%). Perineural invasion was found in 20 cases (54%) and blood vessel and/or lymphatic invasion in 13 (35%). Conclusion: The analysis of data relating to periampullary tumors and patients undergoing gastroduodenopancreatectomy surgery contributes to reinforcing epidemiological knowledge of these conditions, aiming at better patient care.
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Neuman et al. (2025) studied this question.
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