Cascade reaction converts o-aminophenyl propargyl alcohols into sulfinylated and sulfonylated indoles, indicating versatile synthetic pathways.
The cascade reaction of o-aminophenyl/o-hydroxyphenyl propargyl alcohols with β-sulfinyl esters was explored under basic conditions. o-Aminophenyl propargyl alcohols were converted to 3-sulfinyl indoles using KOH, while 3-sulfonyl indoles were obtained...
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Bian et al. (2025) studied this question.
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