Analysis suggests higher buprenorphine doses may improve outcomes in opioid use disorder patients, indicating a potential shift in treatment practices.
Because of the potency of illicit fentanyl, it has been suggested that patients who present for treatment for opioid use disorder (OUD) be given higher doses of buprenorphine than the standard dose. For the same reason, it has been suggested that methadone is a better treatment medication than buprenorphine (see ADAW https://onlinelibrary.wiley.com/doi/10.1002/adaw.34358 ).
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Alison Knopf (2025) studied this question.
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