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August 22, 2025Frontiers in PharmacologyOpen Access

Loperamide poisoning resulting in death: a case report and literature review

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Authors

BWBowen WangZZZhan ZhangKCKe Chen

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Overview

Case report highlights loperamide poisoning leading to death in a teenager, indicating cardiotoxic effects and central nervous system concerns.

Key Points

  • Loperamide poisoning resulted in death due to cardiotoxicity and irreversible brain damage, raising awareness.
  • The patient ingested 60 mg of loperamide before facing cardiac and respiratory arrest, ultimately showing QTc prolongation.
  • Assessment method involved reviewing literature alongside a case report discussing clinical manifestations and treatment.
  • This case underlines the dangers of loperamide overdose, suggesting clinicians need heightened awareness of its effects.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68af541fad7bf08b1eadb8achttps://doi.org/10.3389/fphar.2025.1597869
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