PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
January 1, 2016Journal of Clinical Toxicology

Conduction Disturbances and Ventricular Arrhythmias Associated with High- Dose Loperamide

View Full Paper
Ask AI
Bookmark
Share

Population

A patient presenting with high-dose loperamide ingestion

Design

Case_report

Key result

High-dose loperamide ingestion was associated with unstable bradycardia, polymorphic ventricular tachycardia, and the unmasking of a Brugada ECG pattern in a single patient.

Authors

GLGalen LeungDADiana Altshuler

Discussion

Loading...

Member takes

Overview

May prompt ECG vigilance in loperamide overdose; hypothesis-generating for Brugada unmasking and arrhythmia risk.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A single patient presenting with high-dose loperamide ingestion leading to unstable bradycardia, polymorphic ventricular tachycardia, and an unmasked Brugada ECG pattern.
E
Exposure
High-dose loperamide ingestion
O
Outcome
Conduction disturbances, ventricular arrhythmias, and unmasked Brugada ECG patternsafety

High-dose loperamide abuse can lead to severe cardiac toxicity, including life-threatening ventricular arrhythmias and the unmasking of a Brugada ECG pattern.

Cite This Study

Leung et al. (2016) conducted a case report in High-dose loperamide toxicity (n=1). High-dose loperamide was evaluated. High-dose loperamide ingestion was associated with unstable bradycardia, polymorphic ventricular tachycardia, and the unmasking of a Brugada ECG pattern in a single patient.

synapsesocial.com/papers/6a7506e2cbb3fa1e5bdbd93dhttps://doi.org/10.4172/2161-0495.1000309
View Full Paper
Ask AI
Bookmark
Share