Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 22, 2025Frontiers in PharmacologyOpen Access

Potential therapeutic benefits of curcumin in depression or anxiety induced by chronic diseases: a systematic review of mechanistic and clinical evidence

View Full Paper
Ask AI
Bookmark
Share

Authors

JYJiyuan YuanCPChao PiHSHongping Shen

Discussion

Loading...

Member takes

Overview

Systematic review demonstrates curcumin's significant effects on depression and anxiety symptoms in chronic diseases, indicating its potential as a treatment.

Key Points

  • Curcumin significantly reduces depressive symptoms in patients with chronic diseases, improving their overall quality of life.
  • In meta-analysis, curcumin displayed a standardized mean difference of -0.65 for depression and -0.22 for anxiety using data from 15 RCTs with 1,123 participants.
  • This systematic review employs a meta-analysis approach, combining both clinical trial and preclinical data to explore curcumin's efficacy and mechanisms.
  • These findings support curcumin as a complementary treatment for depression and anxiety, though variability in studies and treatment may limit conclusions.

Cite This Study

Yuan et al. (2025) studied this question.

synapsesocial.com/papers/68af55c6ad7bf08b1eadbc56https://doi.org/10.3389/fphar.2025.1638645
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pathophysiological mechanisms of post-myocardial infarction depression: a narrative review2023 · 38 citations
  2. 2Relationship Between Depression and Medication Adherence Among Chronic Disease Patients in the Middle East2024 · 5 citations
  3. 3Depression and anxiety in patients with different rare chronic diseases: A cross-sectional study2019 · 119 citations
  4. 4Curcumin Alleviates Oxaliplatin-Induced Peripheral Neuropathic Pain through Inhibiting Oxidative Stress-Mediated Activation of NF-κB and Mitigating Inflammation2019 · 76 citations