Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 19, 2025Journal of NeuroscienceOpen Access

Multivariate white matter microstructure alterations in older adults with coronary artery disease

View Full Paper
Ask AI
Bookmark
Share

Authors

STStéfanie TremblayZPZacharie Potvin-JutrasDSDalia Sabra

Discussion

Loading...

Member takes

Overview

Analysis shows significant white matter microstructure differences in individuals with coronary artery disease, suggesting potential links to cognitive decline.

Key Points

  • Patients with coronary artery disease exhibit marked increases in white matter microstructure alterations, indicating potential cognitive risks,
  • A notable finding was that myelin-sensitive metrics like R1 relaxation rate contributed significantly to white matter differences,
  • Utilizing advanced imaging techniques, the study compared 43 patients with coronary artery disease to 36 healthy controls,
  • These findings highlight the connection between coronary artery disease and cognitive decline, underscoring the need for early detection.

Cite This Study

Tremblay et al. (2025) studied this question.

synapsesocial.com/papers/68af55d8ad7bf08b1eadc6edhttps://doi.org/10.1523/jneurosci.0790-25.2025
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1White Matter Microstructural Integrity Is Associated with Executive Function and Processing Speed in Older Adults with Coronary Artery Disease2014 · 76 citations
  2. 2Coronary Artery Calcium, Brain Function and Structure2010 · 135 citations
  3. 3Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease2025 · 5 citations
  4. 4Diffusion kurtosis imaging of brain white matter alteration in patients with coronary artery disease based on the TBSS method2024 · 8 citations
  5. 5The links between complex coronary disease, cerebrovascular disease, and degenerative brain disease2012 · 46 citations