August 15, 2025Open Access

The Human Herpes Virus 6 Seroprevalence in pediatric leukemia: A case-control Study

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Case-control study finds higher HHV-6 prevalence in pediatric leukemia patients, suggesting viral reactivation plays a role in immunosuppression.

Children with leukemia showed a significantly higher mean serum level of HHV-6-specific IgG antibodies.
The serum level in leukemia patients was 77.67 compared to 14.89 in controls, indicating a notable difference.
This case-control study analyzed blood samples from 50 leukemia patients and 50 matched healthy controls.
Findings may highlight the significance of HHV-6 reactivation due to immunosuppression in pediatric leukemia cases.

Alkareem et al. (2025) studied this question.

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Case-control study finds higher HHV-6 prevalence in pediatric leukemia patients, suggesting viral reactivation plays a role in immunosuppression.