Case report demonstrates diagnostic challenges of NSAID-induced colonic mass, implying risk for misdiagnosis.
This case report describes a rare occurrence of nonsteroidal anti‐inflammatory drugs (NSAID)–induced focal colonic granulomatous mass mimicking a malignant colonic mass. It highlights the diagnostic challenges of NSAID‐related gastrointestinal complications and stresses the importance of considering such causes in similar presentations. Prompt recognition and withdrawal of the offending NSAID can prevent unnecessary surgical intervention and facilitate symptom resolution. This case underscores the value of a detailed medication history and cautious NSAID use to reduce the risk of adverse gastrointestinal effects.
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Mekontso et al. (2025) studied this question.
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