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August 21, 2025FoodsOpen Access

Alleviation of Ovalbumin-Allergic Reactions in Mice by Eucommia ulmoides Polysaccharides via Modulation of Intestinal Microbiota

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Authors

XZX ZhangKBKai BiCZChuansheng Zhao

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Overview

Observational analysis revealed reduced allergy scores in allergic mice treated with eucommia ulmoides polysaccharides, indicating potential dietary applications.

Key Points

  • The allergy scores in the OVA+PS group were significantly lower than those in the OVA group, improving allergic responses.
  • Analysis showed that eucommia ulmoides polysaccharides effectively mitigated inflammation in liver, kidney, spleen, and intestinal tissues.
  • Using 16S rDNA sequencing, treatment led to modulation of intestinal microbiota, increasing beneficial currents while reducing harmful bacteria.
  • The study highlights the correlation between microbiota changes and gene expression related to allergy, supporting dietary therapy strategies.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68af56f4ad7bf08b1eadd01ehttps://doi.org/10.3390/foods14162913
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of dietary Eucommia ulmoides oliver polysaccharide on immune function and meat quality of Songliao Black Pigs2024 · 4 citations
  2. 2Mulberry leaf polyphenols alleviate food allergy and moderate intestinal flora and lipid metabolism in allergic mice2026 · 1 citations
  3. 3The alleviated symptoms in ovalbumin‐allergic mice treated with selenium‐enriched tea polysaccharide by modulation of intestinal flora and gut metabolites2024 · 5 citations
  4. 4Eucommia polysaccharides alleviate experimental colitis by reshaping colonic microbiota composition, metabolites, and modulating the IL-17 signaling pathway2026 · 1 citations
  5. 5Impact of ovalbumin allergy on oral and gut microbiome dynamics in 6-week-old BALB/c mice2024 · 7 citations